RALOXIFENE (Evista) is used for treating and preventing osteoporosis (bone thinning) in women who are past menopause. It is also used to reduce the risk of invasive breast cancer in certain women who are past menopause. It may also be used for other conditions as determined by your doctor.
This medicine is a selective estrogen receptor modulator (SERM). It works in osteoporosis by decreasing bone breakdown and thinning that may occur in women after menopause. It works to decrease the risk of invasive breast cancer by blocking estrogen in breast and uterine tissue.
RALOXIFENE reduces the amount of calcium lost from bones. It helps to prevent bone loss and to increase normal healthy bone formation in patients with osteoporosis. It also blocks the effects of estrogen in the breast and can be used to prevent certain types of breast cancer.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
cancer
a history of blood clots
low level of blood calcium
heart failure
high level of blood triglycerides
liver disease
vitamin D deficiency
an unusual or allergic reaction to raloxifene, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I take this medicine?
Raloxifene tablets are taken by mouth. They can be taken with or without food. Follow the directions on the prescription label. Swallow the tablets with a full glass of water. Do not take your medicine more often than directed.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What drug(s) may interact with raloxifene?
ampicillin
thyroid hormones like levothyroxine
herbal or dietary supplements like black cohosh or soy
Tell your prescriber or health care professional about all other medicines you are taking including non-prescription medicines. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These can affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What side effects might I notice from taking raloxifene?
Side effects that you should report to your prescriber or health care professional as soon as possible: Rare or uncommon:
difficulty breathing
leg pain or swelling
skin rash, itching
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
difficulty sleeping
fluid build-up
hot flashes
leg cramps
muscle aches
sinus pressure or drainage
stomach or intestinal gas
stomach pain
sweating
weight gain
What should I watch for while taking raloxifene?
Visit your prescriber or health care professional for regular checks on your progress. Do not stop taking raloxifene except on your prescriber's advice.
You should make sure you get enough calcium and vitamin D in your diet while you are taking raloxifene. Discuss your dietary needs with your health care professional or nutritionist.
Exercise may help to prevent bone loss. Discuss your exercise needs with your prescriber or health care professional.
Raloxifene can rarely cause blood clots. You should avoid long periods of bed rest while taking raloxifene. If you are going to have surgery, tell your prescriber or health care professional that you are taking raloxifene. Raloxifene should be stopped at least 3 days before surgery. After surgery, it should be restarted only after you are walking again. It should not be restarted while you still need long periods of bed rest.
You should not smoke while taking raloxifene. Smoking may also increase your risk of blood clots. Smoking can also decrease the effects of raloxifene on bone.
Where can I keep my medicine?
Keep out of the reach of children in a container that small children cannot open.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
What is the shelf life of the pills?
The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
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What is a generic drug?
A generic drug (pl. generic drugs, short: generics) is a drug which is produced and distributed without patent protection. A generic must contain the same active ingredients as the original formulation. In most cases, it is considered bioequivalent to the brand name counterpart with respect to pharmacokinetic and pharmacodynamic properties. By extension, therefore, generics are assumed to be identical in dose, strength, route of administration, safety, efficacy, and intended use.
Facts about generic drugs
It is the chemical compound that makes up drug.
It is manufactured in strict compliance within th FDA guidelines.
It costs less because they don't have to spend R&D advertising.
It works identical to brand name Drugs to treat a medical condition.
Generic drugs generally cost 30-50% less then the equivalent.
Half of all prescription drugs have generic equivalents.
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