OLANZAPINE (Zyprexa) is used for treating schizophrenia or bipolar disorder.
Olanzapine is an atypical antipsychotic. Exactly how it works is not known. It is thought to affect certain substances in the brain.
OLANZAPINE (Zyprexa®) helps to treat emotional and mental problems like schizophrenia or psychosis. Olanzapine is also sometimes used for the treatment of other emotional or behavioral problems like manic-depressive illness or bipolar disorder. Olanzapine can help you to keep in touch with reality and reduce your mental problems. It is not a cure. Generic olanzapine tablets are not yet available.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
frequently drink alcoholic beverages
breast cancer
cigarette smoker
diabetes mellitus, high blood sugar or a family history of diabetes
difficulty passing urine
glaucoma
heart disease, irregular heartbeat, or previous heart attack
high blood pressure treated with medication
kidney or liver disease
low blood pressure
Parkinson's disease
prostate trouble
seizures (convulsions)
an unusual or allergic reaction to olanzapine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I take this medicine?
Take olanzapine tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. You can take olanzapine with food or meals if you want to. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your prescriber's advice.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
If you miss a dose of olanzapine by a few hours, take the dose when you remember. If most of the day has passed, wait until your next scheduled dose. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What drug(s) may interact with olanzapine?
alcohol
carbamazepine
cimetidine
cisapride
clozapine
donepezil
erythromycin or clarithromycin
fluvoxamine
ketoconazole
levodopa and other medicines for Parkinson's disease
lithium
medicines for colds, hay fever, or allergies
medicines for diabetes
medicines for high blood pressure
medicines for mental depression, anxiety, other mood disorders, or sleeping problems
phenobarbital
rifampin
ritonavir
some medicines for pain (examples: codeine, morphine)
some medicines for gastrointestinal spasm
tacrine
tobacco in cigarrettes
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What side effects may I notice from taking olanzapine?
Side effects that you should report to your prescriber or health care professional as soon as possible: More Common:
agitation or hostile, angry behavior
changes in emotions or behavior, like a very depressed mood
restlessness or need to keep moving
stiffness, spasms
tremors or trembling Rare or Less common:
changes in vision, inability to control eye movements
confusion
difficulty breathing
difficulty concentrating
difficulty in speaking or swallowing
excessive thirst and/or hunger
fainting spells, loss of balance
fast heartbeat (palpitations)
frequently needing to urinate
inability to control muscle movements in the face, hands, arms, or legs
menstrual changes
painful erections
seizures (convulsions)
skin rash
swelling of face or legs
uncontrollable tongue or chewing movements, smacking lips or puffing cheeks
unusual tiredness or weakness
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): Less common or rare:
blurred or unclear vision
changes in sexual desire
excessive drainage from eyes
excessive watering or drooling of mouth
joint pain
nausea or vomiting
sensitivity of skin to sunlight
tingling sensation in your hands, feet or other area of your body
trouble in controlling urine More Common:
constipation
dizziness; especially on standing from a sitting or lying postion
drowsiness
dry mouth
lowered blood pressure
runny nose
weight gain
What should I watch for while taking olanzapine?
Visit your prescriber or health care professional for regular checks on your progress. It may be several weeks before you see the full effects of olanzapine. Do notify your prescriber if your symptoms get worse or you have new symptoms, if you are having an unusual effect from olanzapine, or if you feel out of control, very discouraged or think you might harm yourself or others. Your prescriber can help you manage these problems.
Do not suddenly stop taking olanzapine. You may need to gradually reduce the dose. Only stop taking olanzapine on your prescriber's advice.
You may get dizzy or drowsy. Do not drive, use machinery, or do anything that needs mental alertness until you know how olanzapine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
Alcohol can increase dizziness and drowsiness with olanzapine. Avoid alcoholic drinks.
Do not treat yourself for colds, diarrhea or allergies. Ask your prescriber or health care professional for advice, some nonprescription medicines may increase possible side effects.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help. Be careful when brushing and flossing your teeth to avoid mouth infections or damage to your gums. See your dentist regularly. Sometimes olanzapine can make your mouth water a lot.
Olanzapine can reduce the response of your body to heat or cold. Try not to get overheated or dehydrated from exercise. Avoid temperature extremes, such as saunas, hot tubs, or very hot or cold baths or showers. Dress warmly in cold weather.
Olanzapine may make your skin more sensitive to sun or ultraviolet light. Limit your sun exposure; wear protective clothing outdoors and use a sunscreen (at least SPF 15). Avoid using sun lamps or sun tanning beds or booths.
If you are going to have surgery tell your prescriber or health care professional that you are taking olanzapine.
Where can I keep my medicine?
Keep out of the reach of children in a container that small children cannot open.
Store at controlled room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.
What is the shelf life of the pills?
The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
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What is a generic drug?
A generic drug (pl. generic drugs, short: generics) is a drug which is produced and distributed without patent protection. A generic must contain the same active ingredients as the original formulation. In most cases, it is considered bioequivalent to the brand name counterpart with respect to pharmacokinetic and pharmacodynamic properties. By extension, therefore, generics are assumed to be identical in dose, strength, route of administration, safety, efficacy, and intended use.
Facts about generic drugs
It is the chemical compound that makes up drug.
It is manufactured in strict compliance within th FDA guidelines.
It costs less because they don't have to spend R&D advertising.
It works identical to brand name Drugs to treat a medical condition.
Generic drugs generally cost 30-50% less then the equivalent.
Half of all prescription drugs have generic equivalents.
By asking your pharmacist for generics, you may save a lot.
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